Dr Li-Anne Lim
MBBS BSc (Med) M.Med (Ophth Sc) FRANZCODr Li-Anne Lim is a fellowship trained ocular oncologist who is highly experienced in treating eye cancer in adults and children. She is also skilled in performing cataract surgery and providing general eye care.
Dr Lim completed her medical degree at the University of New South Wales and a Master's in Clinical Ophthalmology at the University of Sydney. She completed her ophthalmology training at Sydney Eye Hospital and was the professorial registrar in her final year of training. She went on to pursue advanced training in diagnosing and managing eye tumours through fellowships at McGill University in Montreal, Canada, and Wills Eye Hospital in Philadelphia, USA.
Dr Lim is actively involved in teaching and research as a clinical associate lecturer at the University of Sydney and has contributed to numerous medical publications and international conferences. She is a member of the International Society of Ocular Oncology and participates in multidisciplinary meetings for eye cancer treatment at The Kinghorn Cancer Centre, St Vincent's Hospital. She is the ophthalmology chair of the Australasian Ocular Melanoma Alliance.
In addition to her work at Sydney Eye Hospital and The Children's Hospital Westmead, Dr Lim is also involved in clinical trials for patients with uveal melanoma in collaboration with the medical oncologists from the Kinghorn Cancer Centre.
Along with Dr Michael Giblin, Dr Lim is committed to providing the best possible care for patients with eye cancer, drawing from their extensive combined experience in ocular oncology, cataract surgery, and general eye care.
Qualifications
- Fellow of the Royal Australian and New Zealand College of Ophthalmologists FRANZCO (Sydney Eye Hospital) 2019
- Fellowship in Ocular Oncology (Wills Eye Hospital, Philadelphia, USA) 2018
- Fellowship in Ocular Pathology (Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Canada) 2012
- Master of Medicine (Ophthalmic Science) - M. Med (Ophth Sc) (USyd) 2010
- Bachelor of Medicine & Bachelor of Surgery- MB BS B Sc (Med) (UNSW) 2007
Memberships
- Fellow of the Royal Australian and New Zealand College of Ophthalmologists
- Australasian Ocular Melanoma Alliance
- International Society of Ocular Oncology
Articles & Podcasts
Understanding ocular melanoma >
An interview with Dr Lim by the Melanoma & Skin Cancer Advocacy NetworkInside the clinical speciality of ocular oncology >
An article written by Rhiannon Bowman for Insight
Publications
- Lim L, Chindasub P, Kitnarong N. The Surgical Outcome of Primary Trabeculectomy with Mytomycin C and A Fornix-Based Conjunctival Technique in Thailand, J Med Assoc Thai 2008;9(10):1551-7
- Maloney SC, Antecka E, Granner T, Fernandes B, Lim LA, Orellana ME, Burnier MN Jr. Expression of SIRT1 in choroidal neovascular membranes. Retina. 2013 Apr;33(4):862-6. doi:10.1097/IAE.0b013e31826af556.
- Maloney S, Antecka E, Odashiro A, Fernandes BF, Doyle M, Lim L, Katib Y, Huynh A, Burnier MN Jr. Expression of SIRT1 and DBC1 in developing and adult retinas, Stem Cells Int. 2012;2012:908183. doi:10.1155/2012/908183. Epub 2012 Aug 30
- Blanco P, Lim L, Myomoto C, Burnier MN Jr. Uveal melanoma dormancy: an acceptable clinical endpoint? Melanoma Res. 2012 Oct;22(5):334-40. doi:10.1097/CMR.0b013e328357bea8.
- Lim L, Madigan MC, Conway RM. Conjunctival melanoma: conceptual and treatment advances, Clinical Ophthalmology 2013:7: 521-531 doi:10.2147/OPTH.S38415
- Lim L, Miyamoto C, Blanco P, Bakalian S, Burnier MN. Case report: an atypical peripapillary uveal melanoma. BMC Ophthalmology 2014 14:13 doi:10.1186/1471-2415-14-13
- Lim LS, Fernandez-Sanz G, Levasseur S et al. Idiopathic full thickness macular hole in a 10-year-old girl. Int J Retina Vitreous. 2018 Jul 11;4:25. doi:10.1186/s40942-018-0128-9. eCollection 2018.
- Lim LA, Williams Jr. BK, Shields CL. Pretty peachy. Indian J Ophthalmol 2018;66:1238.
- Lim LA, Brower P, Shields JA, Shields CL. Episcleral Racemose Hemangioma. J AAPOS. 2018 Nov 20. pii: S1091-8531(18)30574-3. doi:10.1016/j.jaapos.2018.10.007. [Epub ahead of print]
- Gupta R, Fung AT, Lupidi M, Pappuru RR, Nayak S, Sahoo NK, Kaliki S, Yannuzzi L, Reid K, Lim L, Sacconi R, Dave V, Singh SR, Ayachit A, Gabrielle PH, Cai S, Lima L, Querques G, Arevalo JF, Freund KB, Shields CL, Chhablani J. Peripapillary versus macular combined hamartoma of the retina and retinal pigment epithelium: Imaging characteristics. Am J ophthalmol 2019 doi:10.1016/j.ajo.2019.01.016
- Shields CL, Lim LS, Dalvin LA, Shields JA. Small choroidal melanoma: detection with multimodal imaging and management with plaque radiotherapy or AU-011 nanoparticle therapy. Curr Opin Ophthalmol. 2019 May;30(3):206-214. doi:10.1097/ICU.0000000000000560. PMID: 30844944.
- Shields CL, Udyaver S, Dalvin LA, Lim LS, Atalay HT, Khoo C, Mazloumi M, Shields JA. Visual acuity outcomes in Coats disease by classification stage in 160 patients. Br J Ophthalmol 2019 Jun 8. [ePub ahead of print]
- Shields CL, Udyaver S, Dalvin LA, Lim LS, Atalay HT, Khoo C, Mazloumi M, Shields JA. Coats disease in 351 eyes. Analysis of features and outcomes, over 45 years (by decade) at a single centre. Indian J Ophthalmol 2019 Jun;67(6):772-783. doi:10.4103/ijo.IJO_449_19.
- Lim LL, Hasanuzzaman MK, Shields CL. The second time around. Indian J Ophthalmol 2019;67:987.
- Whist E, Symes RJ, Chang JH, Chowdhury V, Lim LA, Grigg JR, Lin ML, Karaconji T, Giblin M, Symons A, Lim LL, McCluskey PJ. UVEITIS CAUSED BY TREATMENT FOR MALIGNANT MELANOMA: A CASE SERIES. Retinal Cases Brief Rep. 2021 Nov 1;15(6):718-723. doi:10.1097/ICB.0000000000000876. PMID: 31274846; PMCID: PMC8542090.
- Dalvin LA, Lim LS, Chang M, Udyaver S, Mazloumi M, Vichitvejpaisal P, Su GL, Florakis E, Mashayekhi A, Shields JA, Shields CL. Circumscribed choroidal hemangioma. Clinical features and outcomes by age category in 458 cases. Saudi Journal of Ophthalmology. In press 2019
- Khoo CTL, Dalvin LA, Lim LS, Mazloumi M, Atalay HT, Udyaver S, Shields JA, Shields CL. Factors Predictive of Subretinal Fluid Resolution in Coats Disease: Analysis of 177 Eyes in 177 Patients at a Single Center. Asia Pac J Ophthalmol (Phila). 2019 Jul 27. doi:10.1097/APO.0000000000000246. [Epub ahead of print]
- Udyaver S, Dalvin LA,Lim LS, Mazloumi M, Atalay HT, Khoo CTL, Shields JA, Shields CL. Predictors of enucleation in Coats disease: analysis of 259 eyes of 259 patients at a single center. J AAPOS. 2019 Oct;23(5):266.e1-266.e9. doi:10.1016/j.jaapos.2019.05.015. Epub 2019 Sep 12.
- Shields CL, Dalvin LA, Lim LS, Chang M, Udyaver S, Mazloumi M, Vichitvejpaisal P, Su GL, Florakis E, Mashayekhi A, Shields JA. Circumscribed Choroidal Hemangioma: Visual Outcome in the Pre-Photodynamic Therapy Era versus Photodynamic Therapy Era in 458 Cases. Ophthalmol Retina. 2020 Jan;4(1):100-110. doi:10.1016/j.oret.2019.08.004. Epub 2019 Aug 22. PMID: 31611094.
- Lim, L-AS, Dalvin, LA, Ancona-Lezama, D, Yu, MD, Jabbour, P, Shields, CL. Retinoblastoma vascular perfusion and intra-arterial chemotherapy cycle requirements. Clin Experiment Ophthalmol. 2019; 47: 1164– 1172. doi:10.1111/ceo.13616
- Su GL, Lim LS, Welch RJ, Shields CL. Retinoblastoma regression following intra-arterial chemotherapy to the contralateral eye. Saudi J Ophthalmol. 2019 Jul-Sep;33(3):291-293. doi:10.1016/j.sjopt.2019.05.007. Epub 2019 Jul 16. PMID: 31686972; PMCID: PMC6819715.
- Yaghy A, Lim LA, Mashayekhi A, Shields CL. BAP1 GERMLINE MUTATION WITH IRIDOCILIOCHOROIDAL MELANOMA AND MALIGNANT PERITONEAL MESOTHELIOMA. Retinal Cases Brief Rep. 2019 Dec 31. doi:10.1097/ICB.0000000000000934. Epub ahead of print. PMID: 31895725.
- Lim LS, Dalvin LA, Ancona-Lezama D, Yu MD, Jabbour P, Shields CL. Retinoblastoma vascular perfusion and intra-arterial chemotherapy cycle requirements. Clin Exp Ophthalmol. 2019 Dec;47(9):1164-1172. doi:10.1111/ceo.13616. Epub 2019 Sep 4. PMID: 31432625.
- Camp DA, Dalvin LA, Schwendeman R, Lim LS, Shields CL. Outcomes of neonatal retinoblastoma in pre-chemotherapy and chemotherapy eras. Indian J Ophthalmol. 2019 Dec;67(12):1997-2004. doi:10.4103/ijo.IJO_634_19. PMID: 31755437; PMCID: PMC6896534.
- Yang X, Dalvin LA, Lim LS, Mashayekhi A, Shields JA, Shields CL. Ultra-low-dose (boom-boom) radiotherapy for choroidal lymphoma in three consecutive cases. Eur J Ophthalmol. 2021 Mar;31(2):NP91-NP96. doi:10.1177/1120672119888985. Epub 2019 Nov 24. PMID: 31760781.
- Dalvin LA, Udyaver S, Lim LS, Mazloumi M, Atalay HT, Khoo CTL, Shields CL. Coats Disease: Clinical Features and Outcomes by Age Category in 351 Cases. Journal of Pediatric Ophthalmology and strabismus. 2019, Vol 56, No. 5.
- Udyaver S, Lim LS, Milman T, Mashayekhi A, Shields JA, Shields CL. Intraocular schwannoma with extrascleral extension. European Journal of Ophthalmology. 2020 In Press. doi:10.1177/1120672120920211
- Lim, Li-Anne S. FRANZCO; Camp, David A. MD; Ancona-Lezama, David MD; Mazloumi, Mehdi MD, MPH; Patel, Shail P. BA; McLaughlin, Jonathan W. MS; Ferenczy, Sandor R. CRA; Mashayekhi, Arman MD; Shields, Carol L. MD Wide-Field (15 × 9 mm) Swept-Source Optical Coherence Tomography Angiography Following Plaque Radiotherapy of Choroidal Melanoma: An Analysis of 105 eyes, Asia-Pacific Journal of Ophthalmology: July-August 2020 - Volume 9 - Issue 4 - p 326-334 doi:10.1097/APO.0000000000000282
Mashayekhi A, Dalvin LA, Lim LS, Ancona-Lezama D, Mazloumi M, Chang M, Shields CL, Shields JA. Association of vitreoretinal lymphoma with systemic lymphoma. Retina. 2020. In Press.
- Yang X, Dalvin LA, Mazloumi M, Ferenczy S, Lim LS, Ancona-Lezama D, Shields JA, Mashayekhi A, Shields CL. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FEATURES OF VITREORETINAL LYMPHOMA IN 55 EYES. Retina. 2021 Feb 1;41(2):249-258. doi:10.1097/IAE.0000000000002819. PMID: 32349103.
- Sweid A, Hammoud B, Weinberg JH, Texakalidis P, Xu V, Shivashankar K, Baldassari MP, Das S, Tjoumakaris SI, Shields CL, Lezama DA, Lim LS, Dalvin LA, El Naamani K, Jabbour P. Ophthalmic artery catheterization for retinoblastoma treatment: does reflux affect tumor response? J Neurointerv Surg. 2020 Sep;12(9):915-920. doi:10.1136/neurintsurg-2019-015597. Epub 2020 Apr 9. PMID: 32277036.
- Sweid A, Hammoud B, Texakalidis P, Xu V, Shivashankar K, Baldassari MP, Das S, Tjoumakaris S, Shields CL, Ancona-Lezama D, Lim LS, Dalvin LA, Maamari DJ, Jabbour P. The Use of Alternative Routes for the Delivery of Intra-Arterial Chemotherapy for Retinoblastoma. Neurosurgery. 2020 Oct 15;87(5):956-963. doi:10.1093/neuros/nyaa142. PMID: 32396190.
- Sweid A, El Naamani K, Sajja KC, Hammoud B, Knapp MD, Moylan DD, Joffe D, Morse CE, Habbal D, Weinberg JH, Tjoumakaris SI, Shields CL, Lezama DA, Lim LS, Dalvin LA, Rosenwasser R, Jabbour P. Incidence and predictors of ophthalmic artery occlusion in intra-arterial chemotherapy for retinoblastoma. J Neurointerv Surg. 2021 Jul;13(7):652-656. doi:10.1136/neurintsurg-2020-016759. Epub 2020 Oct 29. PMID: 33122349.
- Sweid A, Hammoud B, Weinberg JH, Texakalidis P, Xu V, Shivashankar K, Baldassari MP, Das S, Ramesh S, Tjoumakaris S, Shields CL, Ancona-Lezama D, Lim LS, Dalvin LA, Jabbour P. Intra-Arterial Chemotherapy for Retinoblastoma in Infants ≤10 kg: 74 Treated Eyes with 222 IAC Sessions. AJNR Am J Neuroradiol. 2020 Jul;41(7):1286-1292. doi:10.3174/ajnr.A6590. Epub 2020 Jun 25. PMID: 32586963; PMCID: PMC7357663.
- Dalvin LA, Lim LS, Ancona-Lezama D, Mazloumi M, Chang M, Pierluigi P, Martinez N, Glass J, Mashayekhi A, Shields CL. Clinical Features Predictive ofSurvival in Patients With Vitreoretinal Lymphoma: Analysis of 70 Patients at a Single Ocular Oncology Center. Asia-Pacific Journal of Ophthalmology. March-April 2020, Vol 9 (2) p110-116.
- Lim LS, Giblin ME. Uveal melanoma in 2020: Does size still matter? Clinical and Experimental Ophthalmology. doi:10.1111/ceo.13805
- Sweid A, Hammoud B, Weinberg JH, Texakalidis, Xu V, Shivashankar K, Baldassari MP, Das S, Ramesh S, Tjoumakaris S, Shields CL, Ancona-Lezama D, Lim LS, Dalvin LA, Jabbour P. Intra-arterial Chemotherapy for Retinoblastoma in Infants. Am J Neuroradiol. In Press. doi:10.3174/ajnr.A6590
- Ly DV, Wang D, Conway RM, Giblin M, Liang S, Lukeis R, Lim LA, Hesson L, Cherepanoff S. Lipid-Producing Ciliochoroidal Melanoma with Expression of HMG-CoA Reductase. Ocular Oncology and Pathology. doi:10.1159/000510393
- Ledesma-Gil G, Essilfie J, Gupta R, Fung AT, Lupidi M, Pappuru RR, Nayak S, Sahoo NK, Kaliki S, Yannuzzi LA, Reid K, Lim L, Sacconi R, Dave V, Singh SR, Ayachit A, Gabrielle PH, Cai S, Lima LH, Querques G, Arevalo JF, Freund KB, Shields CL, Chhablani J. Presumed Natural History of Combined Hamartoma of the Retina and Retinal Pigment Epithelium. Ophthalmol Retina. 2021 Jan 28:S2468-6530(21)00033-6. doi:10.1016/j.oret.2021.01.011. Epub ahead of print. PMID: 33516918.
- Lin V, Chung IY, Toumi E, McKay D, McKenzie J, McKelvie P, Zabih F, Hoffmeister A, Wright D, Ntzaferi A, Wu IJ, Hesson L, Fung A, Lim LA, Wong S, Field A, Earls P, Giblin M, Conway RM, Cherepanoff S. Biopsy for molecular risk stratification in uveal melanoma: Yields and molecular characteristics in 119 patients. Clin Exp Ophthalmol. 2021 Oct 29. doi:10.1111/ceo.14022. Epub ahead of print. PMID: 34714583.
- Bonnet LA, Conway RM, Lim LA. Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) as a Screening Marker for Familial Adenomatous Polyposis (FAP): Systematic Literature Review and Screening Recommendations. Clin Ophthalmol. 2022 Mar 15;16:765-774. doi:10.2147/OPTH.S354761. PMID: 35321042; PMCID: PMC8934868.
- Babak Masoomian, Lauren A. Dalvin, Hamid Riazi-Esfahani, Fariba Ghassemi, Momeneh Azizkhani, Masoud Mirghorbani, Masoud Khorrami-Nejad, Zaynab Sajjadi, Swathi Kaliki, Mandeep S. Sagoo, Lamis Al Harby, Rana’a T. Al-Jamal, Tero T. Kivelä, Michael Giblin, Li-Anne S. Lim, Carol L. Shields. Pediatric ocular melanoma: a collaborative multicenter study and meta-analysis, Journal of American Association for Pediatric Ophthalmology and Strabismus, 2023
- O'Day RF, Conway RM, Lim LA, Giblin M, Cherepanoff S, Joshua A, McKay D, McKenzie JD, Fog LS, Holly P, Shackleton M, Kee D, Philips C, McKelvie P, Bhikoo R, Hadden P, Negretti GS, Sagoo MS, Damato BE, Sia D, McGrath L, Glasson W, Isaacs T, Gillies M, Barthelmes D. The Fight Tumour Blindness Registry: Efficient capture of high-quality real-world data in uveal melanoma. Can J Ophthalmol. 2024 May 26:S0008-4182(24)00137-6. doi:10.1016/j.jcjo.2024.05.006. Epub ahead of print. PMID: 38810958.